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Ayurveda, the science of life, offers a complete solution with medicines, diet and lifestyle. The radical shift occurred in defining health encourages the medical fraternity of modern times to look deeply into empirically evolved Ayurvedic techniques for the maintenance of positive health. In order to diagnose the disease on the basis of Ayurvedic principles, the physician should have to work very hard to know the subtle changes occurring inside the body due to the imbalance of dosha. To become perfect in Ayurvedic diagnosis, the physician needs to understand dosha vikalpa, dhatu vaishamya, agni stithi and nature of ama.