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The objective of Advanced Pharmacology- I is to equip readers with a strong foundation in the principles governing drug action and their clinical significance. Through a systematic approach, this book aims to enhance critical thinking and foster an evidence-based approach to pharmacotherapy. We extend our gratitude to the contributors, researchers, and reviewers who have enriched this work with their expertise. It is our hope that this book will serve as a valuable guide for those dedicated to the field of pharmacology and its application in improving patient outcomes.