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Experimental political science has changed. In two short decades, it evolved from an emergent method to an accepted method to a primary method. The challenge now is to ensure that experimentalists design sound studies and implement them in ways that illuminate cause and effect. Ethical boundaries must also be respected, results interpreted in a transparent manner, and data and research materials must be shared to ensure others can build on what has been learned. This book explores the application of new designs; the introduction of novel data sources, measurement approaches, and statistical methods; the use of experiments in more substantive domains; and discipline-wide discussions about the robustness, generalizability, and ethics of experiments in political science. By exploring these novel opportunities while also highlighting the concomitant challenges, this volume enables scholars and practitioners to conduct high-quality experiments that will make key contributions to knowledge.