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This volume represents the 2010 Jairo Charris Seminar in Algebraic Aspects of Darboux Transformations, Quantum Integrable Systems and Supersymmetric Quantum Mechanics, which was held at the Universidad Sergio Arboleda in Santa Marta, Colombia. The papers cover the fields of Supersymmetric Quantum Mechanics and Quantum Integrable Systems, from an algebraic point of view. Some results presented in this volume correspond to the analysis of Darboux Transformations in higher order as well as some exceptional orthogonal polynomials. The reader will find an interesting Galois approach to study finite gap potentials. This book is published in cooperation with Instituto de Matematicas y sus Aplicaciones (IMA).