3 Review(s)

The second edition of this text and reference contains: a chapter on the design and selection of biomaterials for specific applications; new data on drug release as an example of leaching, as well as the effects of surface treatment of biomaterials and surface succession of serum proteins; additional details on mechanical degradation of composite materials, and the mechanisms and kinetics of absorbable materials; recent information on the complement system and relative contributions of chemical, mechanical and electrical factors to local host response; current legal and regulatory developments, such as the Safe Medical Device Act (1990); a new section on mechanisms of metal management in vivo and on chromium metabolism; and chapters on properties of widely-used biomaterials, and on recognizing clinical symptoms referable to biomaterials.