3 Review(s)

In eukaryotes many vital cellular functions like metabolism, motility, secretion, growth, differentiation are ultimately regulated by protein phosphorylation/dephosphorylation. Extracellular signals which trigger thesechanges control protein kinases and protein phosphatases. It is the aim of this volume to unveil signal networks which connect extracellular signals via second messengers with chages of the phosphorylation state of target proteins.