3 Review(s)

Experts from ten different countries have contributed their detailed knowledge to this two-volume work, Checkpoint Controls and Cancer, which presents a collection of indispensable tools and their application that will further advance our understanding of the intricacies of checkpoint controls. Volume 1, Reviews and Model Systems, contains comprehensive review articles that introduce all of the important components of checkpoint controls, describes their intricate interactions, and highlights the relevance of these processes to the problem of cancer. It also illustrates the advantage of utilizing diverse model systems such as intact human skin or knockout mice as well as Xenopus, Drosophila, Caenorhabditis, and yeast. This collection of proven techniques will benefit all researchers who want to explore new approaches or model systems for the study of checkpoint controls and cancer.