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Today, biochemical process industry demands fast and economic processes for the partitioning and purification of biomolecules that give high yield and high purity of the product. An integral and cost intensive part of these processes is associated with downstream processing for product isolation and purification. The aim of this comprehensive text is to provide an insightful overview of the whole aspects of downstream processing for biochemical product recovery. Intended for undergraduate and postgraduate students of biotechnology and chemical engineering, this self-contained text includes the chapters based on the recent developments in the industry and academics. It covers the importance of the downstream processing in terms of its relevancy to modern days ever-changing consumer needs, process design criteria relevance to set objectives, and physicochemical factors that help to formulate the strategy to develop a configuration among the raw material, methodology and instruments. This overview is followed by different downstream processing steps. The text concludes with the discussion on stabilization of the product to improve the shelf life of the product. Key Features Includes detailed biological, mathematical, chemical and physical aspects of downstream processing. Distinguishes downstream processing from analytical bioseparation. Contains numerous illustrations and solved problems. About The Author Nooralabettu Krishna Prasad, PhD, is Professor, Department of Biotechnology, P.A. College of Engineering, Mangalore, Karnataka. He has nearly two decades of industrial, research and teaching experience. Professor Krishna Prasad is also a recipient of the prestigious award—Century International Quality Era Award—in Gold Category awarded by BID, Spain at Geneva. Table of contents Part 1 Introduction Chapter 1 Downstream Process Technology: An Overview Chapter 2 Bioproduct Purification Chapter 3 Downstream Process Economics Chapter 4 Cost Cutting Strategies In Downstream Processing Industry Chapter 5 Process Design Criteria For Bioproducts Chapter 6 Characteristics of Biological Mixtures Chapter 7 Physicochemical Basis of Bioseparation Part 2 Removal of Insolubles Chapter 8 Cell Disruption Techniques Chapter 9 Filtration Chapter 10 Centrifugation Part 3 Product Identification Techniques Chapter 11 Characterization of The Product Chapter 12 Analysis of The Product Purity Part 4 Product Separation Techniques Chapter 13 Distillation Chapter 14 Liquid–Liquid Extraction Chapter 15 Adsorption Chapter 16 Evaporation Part 5 Product Purification Chapter 17 Precipitation Chapter 18 Membrane Based Separation Process Chapter 19 Chromatography Part 6 Product Resolution Chapter 20 Crystallization Chapter 21 Freeze Drying Bibliography Index