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Gokhru Big known as caltrops and Pedalium Murex, has long been grown for both food and traditional medicine. In North America, however, it is regarded as a pest because of the harm it causes to natural systems. Therefore, a deeper comprehension of the chemistry and potential uses of caltrop may offer suggestions for ways to make use of this aquatic plant. Pedalium murex fruits are abundant in flavonoids and vitamin C that are two powerful antioxidants. Because of its powerful ability to scavenge free radicals, the ethyl acetate fraction from P. murex fruits is important for maintaining human health. The ethyl-acetate fraction has a good antioxidant capacity and reducing power when compared to other fractions, as demonstrated by an in vitro antioxidant activity assay. Additionally, it is said to have a significant ability to neutralise a number of free radicals, including DPPH, nitric oxide, hydrogen peroxide, and hydroxyl radicals.