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Originally published in 1982, this collection of essays provides an integrated overview of the application of nuclear science to astronomy. The book discusses, among other topics, the abundances of the nuclear and chemical species on the Earth and the Moon, in meteorites, in the stars, and in interstellar space. The hypothesis that these species are produced by nuclear reactions is then explored and related to laboratory measurements. Other subjects include the dynamics of supernovae and interdisciplinary relationships between elementary particle physics and cosmology. The essays are dedicated to Professor William A. Fowler and pay tribute to his vast influence on the field.