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Parkinson's disease is a neurodegenerative disorder that affects approximately 1 million persons in the United States. This disease has been a force in the transformation of neurology from a specialty restricted to diagnosis into one with active and controversial therapies. This book is an up-to-date volume presenting hot topics in this actual scenario. Sections include new functional aspects of basal ganglia, little-known environmental factors in the aetiology of the disease, insights into the disease-related neurodegeneration, a critical discussion of current treatments and their limitations, and unexplored neuropsychiatric presentations of the disease.