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The interaction of a fluid with a solid body is a widespread phenomenon in nature, occurring at different scales and different applied disciplines. Interestingly enough, even though the mathematical theory of the motion of bodies in a liquid is one of the oldest and most classical problems in fluid mechanics, mathematicians have, only very recently, become interested in a systematic study of the basic problems related to fluid-structure interaction, from both analytical and numerical viewpoints.Fundamental Trends in Fluid-Structure Interaction is a unique collection of important papers written by world-renowned experts aimed at furnishing the highest level of development in several significant areas of fluid-structure interactions. The contributions cover several aspects of this discipline, from mathematical analysis, numerical simulation and modeling viewpoints, including motion of rigid and elastic bodies in a viscous liquid, particulate flow and hemodynamic.