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An authoritative handbook, this volume offers both a comprehensive review of the current science of mindfulness and a guide to its ongoing evolution. Leading scholars explore mindfulness in the context of contemporary psychological theories of attention, perceptual processing, motivation, and behavior, as well as within a rich cross-disciplinary dialogue with the contemplative traditions. After surveying basic research from neurobiological, cognitive, emotional/affective, and interpersonal perspectives, the book delves into applications of mindfulness practice in healthy and clinical populations, reviewing a growing evidence base. Examined are interventions for behavioral and emotion dysregulation disorders, depression, anxiety, and addictions, and for physical health conditions.