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Sepsis is a life threatening reaction to an infection. It happens when the body's immune system overreacts to an infection and starts to damage its own tissues and organs. This handbook provides up-to-date strategies in sepsis management for physicians, surgeons, anaesthetists and critical care trainees. The book caters to the need for understanding sepsis evolution, from initial presentation, various early diagnosis techniques and imaging, to organ dysfunction, management aspects and future therapies. Comprising six sections and 23 chapters, the comprehensive text is authored by an experienced multidisciplinary team specialising in the fields of infectious diseases, microbiology and critical care medicine.