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This book presents original results on the leading edge of cancer research. Topics discussed include the risk factors, diagnosis and treatment options for glioblastoma; the biology of the interleukin-2 (il-2)-based immunotherapies in cancer and autoimmune disease; rna interference (rnai)/rna activation (rnaa) for cancer therapeutics; melanoma progression to metastatic disease; proteins, polysaccharide-peptide complexes and polysaccharides with antiproliferative and anticancer activities of mushrooms; low-molecular-weight compounds with anticancer activity of mushroom origin; lifestyle and cancer prevention; and the pathology and pathogenesis of Hodgkin's lymphoma.