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This book is the proceedings of the Falk Symposium 158, on Intestinal Inflammation and Colorectal Cancer, held in March 2007. It covers the current understanding of inflammation-driven colon carcinogenesis, highlights the most relevant mechanisms and discusses measures to interfere with this process. This is a true translational topic which will attract both basic scientists and clinicians, specifically those who can make a difference in preventing this type of cancer.