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Madhumeh is a metabolic disease that causes high blood sugar levels. People are unaware about- what are the types of Madhumeh? It is of two types- Type 1 and Type 2. Type 1 is believed to be an autoimmune condition. This means your immune system mistakenly attacks and destroys the beta cells in your pancreas. The damage is permanent. Type 2 starts as resistance. It leads to high blood sugar, which means more than normal blood glucose levels.