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Laser microdissection techniques have revolutionized the ability of researchers and pathologists to carry out molecular analysis on specific normal and diseased cells and fully utilize the power of current molecular technologies, including PCR, microarrays, and proteomics. In Laser Capture Microdissection: Methods and Protocols, readers are provided with practical advice on how to carry out tissue-based laser microdissection successfully in their own laboratories using the various systems available and how best to apply a wide range of molecular technologies. Applications of the laser-microdissected tissue described in the book include PCR in its many different forms and gene expression analysis involving microarrays and proteomics.