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Since its inaugural edition was published in 1970, the "Manual of Clinical Microbiology" has been hailed as the benchmark for excellence among clinical microbiology books. That tradition of quality continues with the publication of the new eighth edition. Greatly expanded and reorganized into two volumes, "MCM" is the definitive resource for the microbiology, epidemiology, and clinical significance of all clinically significant bacteria, viruses, fungi, and parasites. This invaluable text provides all microbiologists, laboratorians, and infectious disease professionals with the authoritative reference for running an effective, state-of-the-art diagnostic laboratory. No other single resource offers extensive, up-to-date information to address both the practical and esoteric questions. "MCM" sets the standard for reliability and day-to-day utility as a reference work for all busy professionals in the diagnostic laboratory and infectious disease communities. Guiding the clinical microbiologist in the selection, performance, and interpretation of laboratory procedures, "MCM" focuses on the when and why of diagnostic procedures, as well as the how.It presents a direct approach to organizing information with thorough but concise treatments of all the major areas of microbiology, including new microbial discoveries, changing diagnostic methods, and emerging therapeutic challenges facing clinicians. New in the 8th Edition two volumes with 141 chapters by 230 authors, 35 per cent of whom are new to MCM 25 per cent of authors represent 20 non-US countries 25 per cent of the more than 14,000 citations were published since 1999 Reorganized to place all relevant chapters together. New chapters covering laboratory information systems, bioterrorism, and storage of microorganisms are in this book. There is expanded coverage of mycobacteria; specimen collection, transport, and processing; reagents, stains, and media; and antimicrobial agents and susceptibility testing. Most current taxonomic, diagnostic, and therapeutic information are included. The key features and benefits definitive reference work for running an effective, state of the art diagnostic laboratory. This book guides the clinical microbiologist in the selection, performance, and interpretation of laboratory procedures.It includes comprehensive summary of all major groups of clinically important microbes, including bacteria, viruses, fungi, and parasites. The interpretation of test results at the end of each organism chapter summarizes the difficult diagnostic decisions and clinical relevance of the tests described. It contains a comprehensive summary of all antimicrobial agents and test methods, and a comprehensive analysis of antibiotic resistance in all major groups of organisms. It also includes a discussion of both NCCLS and international phenotypic methods for assessing antimicrobial susceptibility.