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Now in its Third Edition, this text clearly and concisely presents the physiological principles that are essential to clinical medicine. Outstanding pedagogical features include problem-solving applications of basic principles; conceptual diagrams that help students visualize complex processes; case studies, Clinical Focus boxes, and From Bench to Bedside boxes; a comprehensive glossary; and online USMLE-style questions with answers and explanations. Now completely updated, this edition features new material, new features, and a robust online package to help students and instructors get the maximum impact from their course.