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This book constitutes the refereed proceedings of the 12th International Conference on Modern Information Technology and IT Education, held in Moscow, Russia, in November 2017. The 30 papers presented were carefully reviewed and selected from 126 submissions. The papers are organized according to the following topics: IT-education: methodology, methodological support; e-learning and IT in education; educational resources and best practices of IT-education; research and development in the field of new IT and their applications; scientific software in education and science; school education in computer science and ICT; economic informatics.