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The sixth edition of Modern Pharmacology with Clinical Applications continues our commitment to enlisting experts in pharmacology to provide a textbook that is up-to-date and comprehensive. Designed to be used during a single semester, the book focuses on the clinical application of drugs within a context of the major principles of pharmacology. It is meant to serve students in medicine, osteopathy, dentistry, pharmacy, and advanced nursing, as well as undergraduate students. Salient Features Study Questions: Each chapter includes five to seven examination questions (following the United States Medical Licensing Examination guidelines) with detailed answers to help students test their knowledge of the covered material. Case Studies: Appearing at the end of each chapter, case studies present students with real-life examples of clinical scenarios and require them to apply their knowledge to solve the problem. Refined Focus: In this edition, we chose to focus more on drug classes rather than on individual drugs, eliminate unnecessary detail such as chemical structures, and maintain emphasis on structure &ndashactivity relationships in drug action and development. Updated Information: This edition also includes new information from the clinic and the laboratory. Emerging information has been added within chapters and when appropriate (as in the case of herbal drugs and erectile dysfunction), through the addition of new chapters. With these revisions, we hope we have provided a book that is readable, up-to-date, comprehensive but not exhaustive, and accurate&mdasha text that supplies both students and faculty with a clear introduction to modern pharmacotherapeutics. Table of Contents I. General Principles of Pharmacology II. Drugs Affecting The Autonomic Nervous III. Drugs Affecting The Cardiovascular System IV. Drugs Affecting The Central Nervous V. Therapeutic Aspects of Inflammatory And Selected Other Clinical Disorders