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This book highlights the progresses achieved in the role of nurses in the hospital, critical care unit, community field, hospital, and at home for patient care management in SARS-CoV-2 (COVID-19), especially in the South Asia and the Middle East. Nurses and allied health care professionals play a significant role in preventing and treating the infectious disease pandemic and epidemic that is COVID-19 and, on the front lines of treatment, they suffer an inescapable health risk due to the fact that they must live with, encounter, and accept the hazard of dealing with developing respiratory illnesses. Nurses also endure significant stress, burden, and mental health concerns as a result of worldwide respiratory epidemics. Because of this, nurses require ongoing assistance and training in order to increase their crisis preparation and efficacy while also coping with psychological issues and ensuring their own well-being. This book reflects the experience of Indianand Saudian nurses, develops on COVID-19 stress and challenges and informs on the technologies employed. Nurses' experiences caring for patients with COVID-19 around the world are scarcely documented. The research that has been done so far have mostly focused on the physical and psychological effects of stress. This expands on the role of nurse managers and hospital administration with key stakeholders emphasizing the need of providing support for nurses in their role, especially considering that the positive leadership responsibilities of nurse managers are highly regarded by nurses.