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UV rays, air pollution, chemicals from vehicles, smoke, etc may result in dry and dull skin, uneven skin tone, wrinkles, and fine lines. UV rays make skin dull by inducing eumelanin formation which is a type of melanin pigment. Melanin pigment is of two types eumelanin and pheomelanin. Eumelanin makes skin dull and dark while pheomelanin increases the luminosity of the skin. In addition, UV radiation and air pollution damage the elastin and collagen of the skin through the generation of free radicals (oxidative stress). Elastin and collagen maintain youthful skin by providing the structural strength to the skin. Clinically researched OPITACTM Glutathione is a potent antioxidant that may brighten the skin by increasing the synthesis of pheomelanin and suppresses eumelanin formation. Furthermore, vitamins like Vitamin C and Vitamin E may prevent oxidative stress induced elastin and collagen damage through their antioxidant property. Supplementation of Glutathione, Vitamin C and Vitamin E along with Biotin could be an effective approach for brightening the skin and maintaining its youthfulness.