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This volume contains the proceedings of the workshop on Optimization Theory and Related Topics, held in memory of Dan Butnariu, from January 11-14, 2010, in Haifa, Israel. An active researcher in various fields of applied mathematics, Butnariu published over 80 papers. His extensive bibliography is included in this volume. The articles in this volume cover many different areas of Optimization Theory and its applications: maximal monotone operators, sensitivity estimates via Lyapunov functions, inverse Newton transforms, infinite-horizon Pontryagin principles, singular optimal control problems with state delays, descent methods for mixed variational inequalities, games on MV-algebras, ergodic convergence in subgradient optimization, applications to economics and technology planning, the exact penalty property in constrained optimization, nonsmooth inverse problems, Bregman distances, retraction methods in Banach spaces, and iterative methods for solving equilibrium problems. This volume will be of interest to both graduate students and research mathematicians.