3 Review(s)

Parkinson's disease (PD) is the second most common neurodegenerative disorder and is caused by degeneration and dysfunction of dopaminergic neurons in substantia nigra. The disease usually clinically starts at age 54-60 and the mean duration from diagnosis to death is about 15 years. In this book, the authors study the diagnosis, treatment and prognosis of Parkinson's disease. Topics include palliative care in Parkinson's disease; therapeutic interventions based on the modulation of cellular degradative systems in Parkinson's physiopathology; Parkinson's disease related changes of oscillatory activity in discrimination tasks; Deep Brain Stimulation (DBS) and Parkinson's disease; and the genetic aspects for diagnosis of Parkinson's disease in different populations.