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Numerous experts including ecologists, geneticists, paleontologists and climatologists, investigate the response of terrestrial organisms to changes in their environment. The volume comprises an introductory and a final chapter by the editors as well as another 35 contributions. These are divided into six sections: 1. past environmental changes - the late-Quaternary; 2. spatial responses to past changes; 3. mechanisms enabling spatial responses; 4. evolutionary responses to past changes; 5. mechanisms enabling evolutionary responses; 6. predicted future environmental changes and simulated responses. The overwhelming and unanimous conclusion of all contributors is that forecasted global environmental changes pose a severe threat to the integrity of ecosystems worldwide and to the survival of at least some species.