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"Pharmacology and Pharmacognosy Principles and Applications" is a comprehensive guide exploring the fundamentals of drug action, sources, and therapeutic mechanisms alongside traditional and modern medicine. This book is covering 46 chapters written by various authors that covers biologics, gene therapy, nanopharmacology, pharmacogenomics, and drug-receptor interactions, while also highlighting herbal medicine, marine chemistry, toxicology, and ethnopharmacology. The book discusses clinical trials, pharmacovigilance, adverse drug reactions, and personalized medicine, bridging pharmaceutical advancements with natural therapeutics. With insights into synthetic vaccines, biotransformation, and alternative medicine systems like homeopathy and naturopathy, this resource is essential for students, researchers, and professionals in pharmaceutical sciences.