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The electrical impulses can reduce the pain signals going to the spinal cord and brain, which may help relieve pain and relax muscles. They may also stimulate the production of endorphins, which are the body's natural painkillers. Transcutaneous electrical nerve stimulation is a nonpharmacologic treatment for pain relief. Using a low voltage electrical current, it safely and effectively can reduce pain, allowing you to live a better quality of life. The TENS unit activates sites in the spinal cord and brain stem that utilize muscarinic, opioid, and serotonin receptors.