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This book constitutes the refereed proceedings of the 6th International Workshop on Artificial Intelligence and Pattern Recognition, IWAIPR 2018, held in Havana, Cuba, in September 2018. The 42 full papers presented were carefully reviewed and selected from 101 submissions. The papers promote and disseminate ongoing research on mathematical methods and computing techniques for artificial intelligence and pattern recognition, in particular in bioinformatics, cognitive and humanoid vision, computer vision, image analysis and intelligent data analysis, as well as their application in a number of diverse areas such as industry, health, robotics, data mining, opinion mining and sentiment analysis, telecommunications, document analysis, and natural language processing and recognition.