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Neem oil is obtained from the whole fruit and seeds of the tropical tree Azadirachta indica, also known as the Indian lilac. While this name shows, this tree is indigenous to the Indian subcontinent where it enjoys the status as a sacred tree and cure-all. This medium-sized evergreen tree now has a worldwide distribution, growing wild in almost any kind of soil and terrain in the tropical and subtropical regions of the world. In India, it is commonly cultivated in many home gardens. In the earlier days when it was quite common for every family to have a dozen or more children, a neem tree in the backyard could meet most of their medical needs. Even the wind blowing through the foliage is thought to have healing properties. Neem tree was the common medicine chest that provided effective cures for anything from intestinal worms to skin ailments and fevers. Notwithstanding their sharp flavor, neem twigs crushed at one end served as toothbrushes and the flowers would be used in cooking. Neem oil is a brownish-yellow liquid with a rich garlicky aroma and very sharp flavor. The biochemical compounds contributing to the antifungal, anti-inflammatory, and antipyretic properties of neem oil belong to a group of triterpenoid compounds known as limonoids, which are also found in the citrus family. Nimbolide, Meliantriol, Azadirachtin, Nimbin, and Salannin are some of the limonoids found in neem, the most potent among them being azadirachtin. The insecticidal properties of azadirachtin are well known and have been exploited in many organic pesticides. Each component of the plant, including the bark and the roots, contain these active compounds and has been used extensively in indigenous medicine, but herbal remedies mainly make use of the leaves because of their easy availability.