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Colocynth (Indravaruni, Bitter Apple) is a great herbal plant with many useful properties. It is also known as Citrullus colocynthis. Indravaruni belongs to the family of gourds and a relative of watermelon. It is the native of Africa and India. It is highly drought tolerant, hard, herbaceous vine. This plant can grow annual or perennial. Their stems are irregular and rough to great extent. Leaves are very rough, 5 to 10 cm long, deep three to seven lobed with middle lobe and sinus in open form with triangular shape and many clefts. The upper surface of the leaves are great green but the lower part is somewhat pale. The flowers are of yellow colour, solitary, peduncle, axillary, monoecious and corollas are 5-lobed. Their fruits are kind of pepo fruits that contain various seeds, a hard rind and other characteristics of gourd family. .........