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The application of artificial intelligence methods and the increasing digitalization of the processes in a supply chain contribute the more seamless flow of materials and information. The disturbances in global supply chain during pandemic put pressure on companies to improve the existing operations. The Sustainable Development Goals put pressure on local and global markets to reduce carbon dioxide emissions and to implement a more resource-efficient business model. Integration of physical and cyber systems is necessary to achieve more environmentally friendly, efficient logistics and supply chain operations. This book presents the contemporary issues of sustainability and integration of physical and information flow in supply chain. In the individual chapters, the authors discuss new qualitative and qualitative theoretic methods, models and present case studies from business practice. This book might be a valuable source of knowledge for the academics, PhD students and practitioners to deepen their knowledge in the field of logistics and SCM.