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Kinesiology Tape - Knee pain is one of the most prevalent forms of joint pain. Knee pain generally occurs as the result of one of three causes. Injury, disease and mechanical issues. Injuries are the most common cause of knee pain. There is almost always acute knee pain when people injure their knees, and there is often chronic pain in the knee long after an injury has occurred. Reduce the pain associated with them, and contribute to the healing process. The most common form of disease that causes knee pain is arthritis, and osteoarthritis, which is the degeneration of cartilage in the knee, is the most common form of disease that causes knee pain.