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A Colloquium was held in Orleans on July 5-9, 1982, to cele- brate the 80th birthday of Professor Charles SADRON. This meeting was devoted to the "Structure, Dynamics, Interactions and Evolution of Biological Macromolecules", research areas whose development in France owes so much to Pr. Sadron's efforts. The Colloquium was sponsored by the Centre National de la Recherche Scientifique and the Museum National d'Histoire Naturelle. This book is a collection of the plenary lectures delivered during this scientific meeting together with several contributions from former collaborators of Pro Charles Sadron. Charles Sadron was born in 1902 at Chateauroux, near the center of France. After highschool in his native town he moved to the University of Poitiers where he was graduated in Physics and then ob- tained the Agregation degree in 1926. Appointed as a highschool teacher in Strasbourg, he devoted his spare time to research in magnetism under the direction of Pro P. Weiss. He got his Ph. D. from the Uni- versity of Strasbourg in 1932 and then did a post-doctoral work at Caltech with Pr. Von Karman.Back to France in 1934, he was appoin- ted as Associate Professor at the University of Strasbourg in 1937. His interest in colloidal suspensions and polymers dates back to these ti- mes when he started to study the morphology of chain polymers. When the second world war started, Charles Sadron moved to Clermont-Ferrand with other members of the University of Strasbourg.