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Textbook of Novel Drug Delivery Systems is a comprehensive guide that explores the latest advancements in drug delivery technologies. It provides in-depth knowledge on controlled drug delivery systems, including various formulation approaches based on diffusion, dissolution, and ion-exchange principles. The book covers the essential role of polymers in drug delivery, discussing their classification, properties, and applications in controlled release systems. Microencapsulation is detailed with its advantages, disadvantages, methods, and applications, making it a crucial topic for pharmaceutical formulation scientists. The mucosal drug delivery system section explains bioadhesion principles and buccal delivery considerations. Implantable drug delivery systems, including implants and osmotic pumps, are thoroughly examined for their benefits and limitations. The transdermal drug delivery system chapter discusses skin permeation mechanisms, enhancers, and formulation approaches. Gastroretentive drug delivery systems are explored, covering floating, high-density, and gastroadhesive methods. Nasopulmonary drug delivery is explained with a focus on inhaler formulations, including dry powders, metered doses, nasal sprays, and nebulizers. Targeted drug delivery introduces liposomes, niosomes, nanoparticles, and monoclonal antibodies, highlighting their applications in modern medicine. The ocular drug delivery system section provides insights into intraocular barriers and advanced formulations like ocuserts. Intrauterine drug delivery systems, including intrauterine devices (IUDs), are discussed with their applications and development considerations. This book serves as an essential resource for pharmacy students, researchers, and pharmaceutical professionals, offering both theoretical and practical insights into novel drug delivery technologies. It bridges the gap between traditional drug formulations and cutting-edge advancements, contributing to the development of more effective and patient-friendly therapies.