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Text Book of Pharmacognosy and Phytochemistry – I is a comprehensive and foundational resource designed to provide pharmacy students with a thorough understanding of crude drugs of natural origin and their applications in modern medicine. The book begins with an insightful introduction to Pharmacognosy, covering its definition, historical evolution, scope, and the various natural sources of drugs, including plants, animals, marine organisms, and tissue cultures. It highlights the distinction between organized and unorganized crude drugs such as dried latex, extracts, gums, and oleoresins. The second chapter delves into the systematic classification of crude drugs based on alphabetical, morphological, chemical, pharmacological, and taxonomical criteria, helping students navigate the diversity of natural substances. The book then discusses adulteration, its definition, and examples, stressing the importance of drug purity and quality control. A significant section is devoted to the evaluation of crude drugs, elaborating on organoleptic, microscopic, physical, chemical, and biological methods, along with specialized techniques like quantitative microscopy using lycopodium spore methods and leaf constants.