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Delve into the critical nuances of pharmaceutical agents with "Textbook of Pharmacology-II" an essential resource for understanding the complex interactions of drugs with the cardiovascular, urinary, and endocrine systems. This comprehensive guide begins with a thorough exploration of hemodynamics and electrophysiology, offering foundational knowledge crucial for grasping the mechanisms of heart-related medications. Spanning congestive heart failure therapies to sophisticated anti-hypertensive, anti-anginal, and anti-arrhythmic drugs, this text meticulously dissects each treatment's function. It further delves into the pharmacology of anti-hyperlipidemics, shock therapy drugs, hematinics, as well as coagulants and their counterparts, ensuring a detailed comprehension of blood and its intricacies. The book extends beyond the heart, covering drugs impacting the urinary system, such as diuretics and anti-diuretics, and introduces autacoids, shedding light on substances like histamine, prostaglandins, and more, integral to allergic and inflammatory responses. Inflammation and pain management are addressed through NSAIDs, anti-gout, and antirheumatic drug discussions, while a significant portion is dedicated to endocrine system pharmacology. The text concludes with an insightful section on bioassays, providing practical knowledge on the principles, types, and specific assays for hormones and neurotransmitters like insulin, oxytocin, vasopressin, and serotonin.