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Gender diversity is now recognised as simply part of human diversity, rather than being pathological. This shift calls for a need for mental health professionals to adapt their practice when working with trans and non-binary people. Written by two clinicians with significant experience in this field, this book provides practical, everyday advice on what to do when seeing gender-diverse people in both inpatient and outpatient settings. It avoids focusing on academic theory or being overly political and, instead, offers straightforward, useful guidance on common issues clinicians may face, such as which ward to accommodate someone on or which name to use when. Topics include common drug interactions, differential diagnoses, complex case formulation, autistic spectrum conditions, the spectrum of sexualities, surgeries, legal and religious matters, forensic assessment, psychotherapy and mental health diagnoses. Fully relevant to contemporary practice, this is a much-needed guide for busy clinicians seeking immediate, practical and authoritative answers.