3 Review(s)

amino sugar that is produced naturally in humans. It is also found in seashells, or it can be made in the laboratory. Bone and joint disease called Kashin-Beck disease. Early evidence shows that taking hydrochloride along with chondroitin sulfate reduces pain and improves physical function in adults with a bone and joint disorder called Kashin-Beck disease. •Knee pain. There is some early evidence that hydrochloride might provide some pain relief for people who have frequent knee pain as a result of joint injury. •Osteoarthritis. There is conflicting evidence about the effectiveness of hydrochloride for osteoarthritis. Most of the evidence supporting the use of glucosamine hydrochloride comes from studies of a particular product (CosaminDS, Nutramax Laboratories). This product contains a combination of hydrochloride, chondroitin sulfate, and manganese ascorbate. Some evidence suggests that this combination can improve pain in people with knee osteoarthritis. This combination might work better in people with mild-to-moderate osteoarthritis than in people with severe osteoarthritis. •Most research suggests that taking hydrochloride alone does not reduce pain in people with osteoarthritis of the knee. More research has been done on sulfate (see separate listing) than on hydrochloride. There is some thought that sulfate may be more effective than hydrochloride for osteoarthritis. Most research comparing the two forms of showed no difference. •Rheumatoid arthritis. Early research shows that taking a specific hydrochloride product (Rohto Pharmaceuticals Co.) in combination with prescription medical treatments reduces pain compared to a sugar pill. •Jaw pain (temporomandibular disorder). Early research shows that taking a combination of hydrochloride, chondroitin sulfate, and calcium ascorbate twice daily reduces joint swelling and pain, as well as noise made at the jaw joint, in people with temporomandibular disorder. •Back pain. •Glaucoma. •Weight loss. •Other conditions.