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Stay Healthy Your skin is the largest organ in your body, and it contains a lot of omega-3 fatty acids. Skin health can decline throughout your life, especially during old age or after too much sun exposure. This source of essential fats supports the health and beauty of human skin in several ways. Fish oil benefits and nourishes the skin with fats and contributes fat-soluble vitamins that help skin maintain a smooth, elastic texture. Fish oil and omega-3 supplements may support symptoms of depression. Like your brain, your eyes rely on omega-3 fats. During old age, bones can begin to lose their essential minerals, making them more likely to break. Calcium and vitamin D are very important for bone health, but some studies suggest that omega-3 fatty acids can also be beneficial.