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This book contains a selection of thoroughly refereed and revised papers from the Second International ICST Conference on Wireless and Mobile Communication in Healthcare, MobiHealth 2010, held in Ayia Napa, Cyprus, in October 2010. The 33 papers in this volume describe various applications of information and communication technologies in healthcare and medicine and cover a wide range of topics such as intelligent public health monitoring services, mobile health technologies, signal processing techniques for monitoring services, wearable biomedical devices, ambient assistive technologies, emergency and disaster applications, and integrated systems for chronic monitoring and management.