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Sleep disorders are not uncommon major public health problem, studies revealed that sleep disorders have emerged as global epidemic and unanimously prevalent across different socio economic status. Chronic sleep deprivation or fragmented sleep causes harmful consequences for both physical and mental health like increased risks of cardiovascular, metabolic and psychiatric disorders, premature cognitive impairments, or even may lead to mortality. For measuring normal sleep and for diagnosing most of the sleep disorders, polysomnography is considered as gold standard test but investigating sleep and sleep related disorders require sound knowledge of sleep physiology, sleep medicine and expertise in sleep technology. So, this book will be an excellent reference guide for the basic concepts about normal sleep and sleep disorders, types of overnight sleep studies, how to approach a subject with suspected sleep disorder, how to prepare a subject for sleep study, electrode placement scoring of events during sleep, test procedures for diagnostic & therapeutic sleep study, manual titration, positive airway pressure therapy and technical information about calibration, artifacts, and various montages. This book will be easy to understand and comprehensive and that one can begin a career in sleep medicine by simply reading it. This book will be helpful for the beginners who want to start carrier in the field of sleep medicine as sleep technologist, sleep physician, researcher or trainee because from this book they will be able to learn more about technical and clinical aspect of evaluating sleep physiology and sleep disorders. Along with post graduate students of various department (Physiology, Pulmonary Medicine, Neurology, Psychiatry, ENT, etc.), this book will also be helpful for Undergraduate students because NMC include the sleep physiology in competency based medical education (CBME).