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Easily understandable introduction in an overview style Practical examples with exercises and solutions At last, here is a baseline book for anyone who is confused by cryptic computer programs, algorithms and formulae, but wants to learn about applied bioinformatics. Now, anyone who can operate a PC, standard software and the Internet can also learn to understand the biological basis of bioinformatics, of the existence as well as the source and availability of bioinformatics software, and how to apply these tools and interpret results with confidence. This process is aided by chapters that introduce important aspects of bioinformatics, detailed bioinformatics exercises (including solutions), and to cap it all, a glossary of definitions and terminology relating to bioinformatics. Table of Contents Computers, operating systems and the Internet The biological foundations of bioinformatics Biological databases Sequence comparisons and sequence-based database searches The decoding of eukaryotic genomes Protein structures and structure-based rational drug design Systems biology – the functional analysis of genomes Comparative genome analyses Solutions to the Exercises Glossary