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This book constitutes the thoroughly refereed proceedings of the International Conference on Communication Technologies for Ageing Well and e-Health, ICT4AWE 2016, held in Rome, Italy, in April 2016. The 8 full papers presented were carefully reviewed and selected from 39 submissions. The papers present relevant trends of current research on ageing well and e-health, including: ambient assisted living, mobile assistive technology, lifestyle engineering and life quality, electronic health records, security and privacy in e-Health, smart environments, home care and remote monitoring.