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This book serves as a foundation for MRI guided laser interstitial thermal therapy (LITT) across neurosurgical diseases. It provides state-of-the-art information on the latest indications and results for LITT in CNS applications, as well as prerequisite historical perspective and technical fundamentals. Written by experts in the field, the text reviews the historical development of LITT, the technical and technological components required to perform LITT, its indications and contraindications, areas that still require investigation, LITT complications, and challenges to starting up LITT within one's practice. As early adopters of the technology, the authors provide sage advice that reflects the initial learning curves of many of the users. The book then concludes with a practical guide to starting up a LITT practice in the current medical socioeconomic environment. Laser Interstitial Thermal Therapy in Neurosurgery is a guide that will allow all neurosurgeons interested in LITT to successfully adopt the technology and incorporate its use seamlessly, safely and appropriately into their individual practices.