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Fully updated and rewritten by Professor Nogrady and Professor Weaver, a basic scientist who is also a practicing physician. the third edition of this popular textbook remains comprehensive, authoritive, and readable. Taking a receptor-based, target-centered approach, it presents the concepts central to the study of drug action in a logical, mechanistic way grounded on molecular and biochemical principles. Students of pharmacy, chemistry, and pharmacology, as well as researchers interested in a better understanding of drug design, will find this book an invaluable resource. About Author : Thomas Nogrady, PhD, is Emeritus Professor of Medicinal Chemistry at Concordia University, Montreal, Quebec, Canada. Donald F. Weaver, MD, PhD, FRCP(c), is the Canada Research Chair and Professor of Medicine and Chemistry at Dalhousie University, Halifax, Nova Scotia, Canada. Contents : General Molecular Principles of Drug Design Introduction to Part I Basic Principles of Drug Design I-Drug Molecules: Structure and Properties Basic Principels of Drug Design II -Receptors: Structure and Properties Messenger Targets for Drug Action III: Immunomodulators and Their Receptors Nonmessenger Targets for Drug Action I: Endoegenous Cellular Structures Nonmessenger Targets for Drug Action II: Endogenous Macromolecules Nonmessenger Targets for Drug Action III: Exogenous Pathogens and Toxins Selected References Appendix: Drugs Arranged by Pharmacological Activity Index